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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006309

Entrez Gene ID

9475

Official Gene Symbol

ROCK2

Synonyms

KIAA0619

Gene name

Rho-associated, coiled-coil containing protein kinase 2

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p24

Known cancer genes

Yes

Protein products

Rho-associated protein kinase 2

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:10252
MIM:604002
Ensembl:ENSG00000134318
HPRD:04922
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000910

cytokinesis

GO:0001843

neural tube closure

GO:0004674

protein serine/threonine kinase activity

GO:0005198

structural molecule activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006468

protein phosphorylation

GO:0007411

axon guidance

GO:0010825

positive regulation of centrosome duplication

GO:0030036

actin cytoskeleton organization

GO:0031616

spindle pole centrosome

GO:0035556

intracellular signal transduction

GO:0046872

metal ion binding