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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006332

Entrez Gene ID

9507

Official Gene Symbol

ADAMTS4

Synonyms

ADAMTSN2|ADAMTSN4|ADMPN1|KIAA0688

Gene name

ADAM metallopeptidase with thrombospondin type 1 motif, 4

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q21-q23

Known cancer genes

Yes

Protein products

A disintegrin and metalloproteinase with thrombospondin motifs 4

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:220
MIM:603876
Ensembl:ENSG00000158859
HPRD:04853
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001501

skeletal system development

GO:0002020

protease binding

GO:0004222

metalloendopeptidase activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0006508

proteolysis

GO:0008233

peptidase activity

GO:0008237

metallopeptidase activity

GO:0008270

zinc ion binding

GO:0046872

metal ion binding