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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006334

Entrez Gene ID

9509

Official Gene Symbol

ADAMTS2

Synonyms

ADAMNTS2|ADAMTSN2|ADAMTSN3|DKFZp686F12218|NPI|PC_INNP|PCINNP|PCINP|PCPNI|PNPI

Gene name

ADAM metallopeptidase with thrombospondin type 1 motif, 2

Gene Type

protein-coding

Chromosome

5

Genomics Location

5qter

Known cancer genes

Yes

Protein products

A disintegrin and metalloproteinase with thrombospondin motifs 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:218
MIM:604539
Ensembl:ENSG00000087116
HPRD:05173
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004222

metalloendopeptidase activity

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0007283

spermatogenesis

GO:0008233

peptidase activity

GO:0008237

metallopeptidase activity

GO:0008270

zinc ion binding

GO:0030199

collagen fibril organization

GO:0030324

lung development

GO:0030574

collagen catabolic process

GO:0043588

skin development

GO:0046872

metal ion binding

GO:0051605

protein maturation by peptide bond cleavage