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Gene basic information

LiverAtlas Gene ID

HuLG006335

Entrez Gene ID

9510

Official Gene Symbol

ADAMTS1

Synonyms

C3NC5|KIAA1346|METH1

Gene name

ADAM metallopeptidase with thrombospondin type 1 motif, 1

Gene Type

protein-coding

Chromosome

21

Genomics Location

21q21.2

Known cancer genes

Yes

Protein products

A disintegrin and metalloproteinase with thrombospondin motifs 1

ADAM metallopeptidase with thrombospondin type 1 motif, 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:217
MIM:605174
Ensembl:ENSG00000154734
HPRD:05530
RefSeq Genomic nucleotide accession:AC_000064
RefSeq Genomic nucleotide gi:89161201

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001542

ovulation from ovarian follicle

GO:0001822

kidney development

GO:0004222

metalloendopeptidase activity

GO:0005576

extracellular region

GO:0005604

basement membrane

GO:0006508

proteolysis

GO:0007229

integrin-mediated signaling pathway

GO:0008201

heparin binding

GO:0008233

peptidase activity

GO:0008237

metallopeptidase activity

GO:0008270

zinc ion binding

GO:0008285

negative regulation of cell proliferation

GO:0031410

cytoplasmic vesicle

GO:0046872

metal ion binding

GO:0060347

heart trabecula formation