HuLG006418

Entrez Gene ID

9619

Official Gene Symbol

ABCG1

Synonyms

ABC8|MGC34313|WHITE1

Gene name

ATP-binding cassette, sub-family G (WHITE), member 1

Gene Type

protein-coding

Chromosome

21

Genomics Location

21q22.3

Known cancer genes

Yes

Protein products

ATP-binding cassette sub-family G member 1

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:73
MIM:603076
Ensembl:ENSG00000160179
HPRD:04355
RefSeq Genomic nucleotide accession:AC_000064
RefSeq Genomic nucleotide gi:89161201

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000139

Golgi membrane

GO:0000166

nucleotide binding

GO:0005524

ATP binding

GO:0005543

phospholipid binding

GO:0005548

phospholipid transporter activity

GO:0005768

endosome

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006355

regulation of transcription, DNA-dependent

GO:0006629

lipid metabolic process

GO:0006810

transport

GO:0008203

cholesterol metabolic process

GO:0009720

detection of hormone stimulus

GO:0009897

external side of plasma membrane

GO:0010033

response to organic substance

GO:0010745

negative regulation of macrophage derived foam cell differentiation

GO:0010872

regulation of cholesterol esterification

GO:0010875

positive regulation of cholesterol efflux

GO:0010887

negative regulation of cholesterol storage

GO:0015485

cholesterol binding

GO:0015914

phospholipid transport

GO:0016887

ATPase activity

GO:0017127

cholesterol transporter activity

GO:0019534

toxin transporter activity

GO:0032367

intracellular cholesterol transport

GO:0033344

cholesterol efflux

GO:0033700

phospholipid efflux

GO:0033993

response to lipid

GO:0034041

sterol-transporting ATPase activity

GO:0034374

low-density lipoprotein particle remodeling

GO:0034375

high-density lipoprotein particle remodeling

GO:0034436

glycoprotein transport

GO:0034437

glycoprotein transporter activity

GO:0042157

lipoprotein metabolic process

GO:0042632

cholesterol homeostasis

GO:0042803

protein homodimerization activity

GO:0042987

amyloid precursor protein catabolic process

GO:0043531

ADP binding

GO:0043691

reverse cholesterol transport

GO:0045542

positive regulation of cholesterol biosynthetic process

GO:0046982

protein heterodimerization activity

GO:0046983

protein dimerization activity

GO:0055037

recycling endosome

GO:0055091

phospholipid homeostasis

GO:0055099

response to high density lipoprotein particle stimulus