HuLG006480

Entrez Gene ID

9693

Official Gene Symbol

RAPGEF2

Synonyms

CNrasGEF|NRAPGEP|PDZNGEF1|PDZGEF1|RANGEF|RapNGEP|nRap_GEP

Gene name

Rap guanine nucleotide exchange factor (GEF) 2

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q32.1

Known cancer genes

Yes

Protein products

RAPGEF2 protein

Putative uncharacterized protein PDZGEF1

Rap guanine nucleotide exchange factor 2

Database cross reference

HGNC:16854
MIM:609530
Ensembl:ENSG00000109756
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

GO annotation

GO:0000165

MAPKKK cascade

GO:0004871

signal transducer activity

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005509

calcium ion binding

GO:0005622

intracellular

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007264

small GTPase mediated signal transduction

GO:0016020

membrane

GO:0017034

Rap guanyl-nucleotide exchange factor activity

GO:0019933

cAMP-mediated signaling

GO:0019992

diacylglycerol binding

GO:0032854

positive regulation of Rap GTPase activity

GO:0035556

intracellular signal transduction

GO:0046582

Rap GTPase activator activity

GO:0051056

regulation of small GTPase mediated signal transduction