Gene basic information
| LiverAtlas Gene ID |
HuLG006598 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ARHGEF11 |
|
Synonyms |
DKFZp667F1223|GTRAP48|KIAA0380|PDZNRHOGEF |
|
Gene name |
Rho guanine nucleotide exchange factor (GEF) 11 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:14580
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000910 |
cytokinesis |
|
GO:0001558 |
regulation of cell growth |
|
GO:0001664 |
G-protein-coupled receptor binding |
|
GO:0004871 |
signal transducer activity |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
|
GO:0005096 |
GTPase activator activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006915 |
apoptosis |
|
GO:0006928 |
cellular component movement |
|
GO:0006941 |
striated muscle contraction |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0007266 |
Rho protein signal transduction |
|
GO:0007411 |
axon guidance |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0030010 |
establishment of cell polarity |
|
GO:0030036 |
actin cytoskeleton organization |
|
GO:0035023 |
regulation of Rho protein signal transduction |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0051056 |
regulation of small GTPase mediated signal transduction |
