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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006609

Entrez Gene ID

9839

Official Gene Symbol

ZEB2

Synonyms

FLJ42816|HSPC082|KIAA0569|SIPN1|SIP1|SMADIP1|ZFHX1B

Gene name

zinc finger E-box binding homeobox 2

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q22.3

Known cancer genes

Yes

Protein products

cDNA FLJ55880, highly similar to Zinc finger homeobox protein 1b

Putative uncharacterized protein ZFHX1B

Putative uncharacterized protein ZFHX1B

Smad interacting-protein 1

Smad interacting-protein 1

Zinc finger E-box-binding homeobox 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:14881
MIM:605802
Ensembl:ENSG00000169554
HPRD:05780
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001755

neural crest cell migration

GO:0001756

somitogenesis

GO:0001843

neural tube closure

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0007399

nervous system development

GO:0007417

central nervous system development

GO:0008270

zinc ion binding

GO:0019208

phosphatase regulator activity

GO:0021766

hippocampus development

GO:0021846

cell proliferation in forebrain

GO:0030177

positive regulation of Wnt receptor signaling pathway

GO:0043507

positive regulation of JUN kinase activity

GO:0043565

sequence-specific DNA binding

GO:0046332

SMAD binding

GO:0046872

metal ion binding

GO:0048598

embryonic morphogenesis