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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006726

Entrez Gene ID

9970

Official Gene Symbol

NR1I3

Synonyms

CAR|CAR1|MB67|MGC150433|MGC97144|MGC97209

Gene name

nuclear receptor subfamily 1, group I, member 3

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q23.3

Known cancer genes

Yes

Protein products

Constitutive androstane receptor

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Constitutive androstane nuclear receptor variant 2

Constitutive androstane nuclear receptor variant 3

Constitutive androstane nuclear receptor

Nuclear receptor subfamily 1 group I member 3

Constitutive androstane nuclear receptor variant 4

Nuclear receptor subfamily 1, group I, member 3

Constitutive androstane receptor SV22

Constitutive androstane receptor SV21

Constitutive androstane receptor SV17

Constitutive androstane receptor SV15

Constitutive androstane receptor SV14

Constitutive androstane receptor SV13

Constitutive androstane receptor SV12

Constitutive androstane receptor SV11

Constitutive androstane receptor SV10

Constitutive androstane receptor SV8

Constitutive androstane receptor SV7

Constitutive androstane receptor SV6

Constitutive androstane nuclear receptor variant 5

Constitutive androstane receptor SV3

Constitutive androstane receptor SV1

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Database cross reference

HGNC:7969
MIM:603881
Ensembl:ENSG00000143257
HPRD:04858
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003713

transcription coactivator activity

GO:0004879

ligand-dependent nuclear receptor activity

GO:0004882

androgen receptor activity

GO:0004887

thyroid hormone receptor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0007165

signal transduction

GO:0008270

zinc ion binding

GO:0010467

gene expression

GO:0030521

androgen receptor signaling pathway

GO:0034339

regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

GO:0043565

sequence-specific DNA binding

GO:0046872

metal ion binding