Gene basic information
LiverAtlas Gene ID |
HuLG006727 |
Entrez Gene ID |
|
Official Gene Symbol |
NR1H4 |
Synonyms |
BAR|FXR|HRRN1|HRR1|MGC163445|RIP14 |
Gene name |
nuclear receptor subfamily 1, group H, member 4 |
Gene Type |
protein-coding |
Chromosome |
12 |
Genomics Location |
12q23.1 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:7967
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
GO:0003707 |
steroid hormone receptor activity |
GO:0003713 |
transcription coactivator activity |
GO:0003714 |
transcription corepressor activity |
GO:0004879 |
ligand-dependent nuclear receptor activity |
GO:0004887 |
thyroid hormone receptor activity |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005654 |
nucleoplasm |
GO:0006351 |
transcription, DNA-dependent |
GO:0006355 |
regulation of transcription, DNA-dependent |
GO:0007165 |
signal transduction |
GO:0008206 |
bile acid metabolic process |
GO:0008270 |
zinc ion binding |
GO:0010467 |
gene expression |
GO:0034339 |
regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor |
GO:0043565 |
sequence-specific DNA binding |
GO:0046872 |
metal ion binding |