Gene basic information
| LiverAtlas Gene ID |
HuLG006759 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
HDAC6 |
|
Synonyms |
FLJ16239|HD6 |
|
Gene name |
histone deacetylase 6 |
|
Gene Type |
protein-coding |
|
Chromosome |
0 |
|
Genomics Location |
Xp11.23 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:14064
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000118 |
histone deacetylase complex |
|
GO:0000209 |
protein polyubiquitination |
|
GO:0003779 |
actin binding |
|
GO:0004407 |
histone deacetylase activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005874 |
microtubule |
|
GO:0005875 |
microtubule associated complex |
|
GO:0005881 |
cytoplasmic microtubule |
|
GO:0005901 |
caveola |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006476 |
protein deacetylation |
|
GO:0006515 |
misfolded or incompletely synthesized protein catabolic process |
|
GO:0006886 |
intracellular protein transport |
|
GO:0007026 |
negative regulation of microtubule depolymerization |
|
GO:0008013 |
beta-catenin binding |
|
GO:0008017 |
microtubule binding |
|
GO:0008270 |
zinc ion binding |
|
GO:0009636 |
response to toxin |
|
GO:0009967 |
positive regulation of signal transduction |
|
GO:0010033 |
response to organic substance |
|
GO:0010469 |
regulation of receptor activity |
|
GO:0010634 |
positive regulation of epithelial cell migration |
|
GO:0010727 |
negative regulation of hydrogen peroxide metabolic process |
|
GO:0010870 |
positive regulation of receptor biosynthetic process |
|
GO:0016234 |
inclusion body |
|
GO:0016235 |
aggresome |
|
GO:0016236 |
macroautophagy |
|
GO:0016568 |
chromatin modification |
|
GO:0016575 |
histone deacetylation |
|
GO:0016787 |
hydrolase activity |
|
GO:0019899 |
enzyme binding |
|
GO:0030286 |
dynein complex |
|
GO:0031252 |
cell leading edge |
|
GO:0031593 |
polyubiquitin binding |
|
GO:0032041 |
NAD-dependent histone deacetylase activity (H3-K14 specific) |
|
GO:0032418 |
lysosome localization |
|
GO:0034739 |
histone deacetylase activity (H3-K16 specific) |
|
GO:0034983 |
peptidyl-lysine deacetylation |
|
GO:0042826 |
histone deacetylase binding |
|
GO:0042903 |
tubulin deacetylase activity |
|
GO:0043014 |
alpha-tubulin binding |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043162 |
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
|
GO:0043242 |
negative regulation of protein complex disassembly |
|
GO:0045861 |
negative regulation of proteolysis |
|
GO:0046872 |
metal ion binding |
|
GO:0046969 |
NAD-dependent histone deacetylase activity (H3-K9 specific) |
|
GO:0046970 |
NAD-dependent histone deacetylase activity (H4-K16 specific) |
|
GO:0048156 |
tau protein binding |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0048487 |
beta-tubulin binding |
|
GO:0051354 |
negative regulation of oxidoreductase activity |
|
GO:0051788 |
response to misfolded protein |
|
GO:0051789 |
response to protein stimulus |
|
GO:0051879 |
Hsp90 protein binding |
|
GO:0060632 |
regulation of microtubule-based movement |
|
GO:0060765 |
regulation of androgen receptor signaling pathway |
|
GO:0070301 |
cellular response to hydrogen peroxide |
|
GO:0070840 |
dynein complex binding |
|
GO:0070842 |
aggresome assembly |
|
GO:0070845 |
polyubiquitinated misfolded protein transport |
|
GO:0070846 |
Hsp90 deacetylation |
|
GO:0070848 |
response to growth factor stimulus |
|
GO:0071218 |
cellular response to misfolded protein |
|
GO:0090035 |
positive regulation of cellular chaperone-mediated protein complex assembly |
|
GO:0090042 |
tubulin deacetylation |
