HuLG006805

Entrez Gene ID

10075

Official Gene Symbol

HUWE1

Synonyms

ARFNBP1|HECTH9|HSPC272|Ib772|KIAA0312|LASU1|MULE|UREB1

Gene name

HECT, UBA and WWE domain containing 1

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xp11.22

Known cancer genes

Yes

Protein products

Uncharacterized protein

Uncharacterized protein

E3 ubiquitin-protein ligase HUWE1

HECT, UBA and WWE domain containing 1

Database cross reference

HGNC:30892
MIM:300697
Ensembl:ENSG00000086758
HPRD:06608
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

GO annotation

GO:0000209

protein polyubiquitination

GO:0003677

DNA binding

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0006284

base-excision repair

GO:0006464

protein modification process

GO:0006513

protein monoubiquitination

GO:0016574

histone ubiquitination

GO:0016874

ligase activity

GO:0016881

acid-amino acid ligase activity

GO:0030154

cell differentiation

GO:0042787

protein ubiquitination involved in ubiquitin-dependent protein catabolic process