Gene basic information
LiverAtlas Gene ID |
HuLG006900 |
Entrez Gene ID |
|
Official Gene Symbol |
TNK2 |
Synonyms |
ACK|ACK1|FLJ44758|FLJ45547|p21cdc42Hs |
Gene name |
tyrosine kinase, non-receptor, 2 |
Gene Type |
protein-coding |
Chromosome |
3 |
Genomics Location |
3q29 |
Known cancer genes |
Yes |
Protein products |
cDNA FLJ45547 fis, clone BRTHA2035743, highly similar to Activated CDC42 kinase 1 (EC 2.7.10.2) |
Related liver disease name |
|
Database cross reference |
HGNC:19297
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0004713 |
protein tyrosine kinase activity |
GO:0004715 |
non-membrane spanning protein tyrosine kinase activity |
GO:0005095 |
GTPase inhibitor activity |
GO:0005515 |
protein binding |
GO:0005524 |
ATP binding |
GO:0005634 |
nucleus |
GO:0005737 |
cytoplasm |
GO:0005768 |
endosome |
GO:0005886 |
plasma membrane |
GO:0005912 |
adherens junction |
GO:0006468 |
protein phosphorylation |
GO:0007264 |
small GTPase mediated signal transduction |
GO:0016310 |
phosphorylation |
GO:0016567 |
protein ubiquitination |
GO:0030054 |
cell junction |
GO:0030659 |
cytoplasmic vesicle membrane |
GO:0031410 |
cytoplasmic vesicle |
GO:0046872 |
metal ion binding |
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |