Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006900

Entrez Gene ID

10188

Official Gene Symbol

TNK2

Synonyms

ACK|ACK1|FLJ44758|FLJ45547|p21cdc42Hs

Gene name

tyrosine kinase, non-receptor, 2

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q29

Known cancer genes

Yes

Protein products

Activated CDC42 kinase 1

cDNA FLJ45547 fis, clone BRTHA2035743, highly similar to Activated CDC42 kinase 1 (EC 2.7.10.2)

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:19297
MIM:606994
Ensembl:ENSG00000061938
HPRD:06104
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0004713

protein tyrosine kinase activity

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO:0005095

GTPase inhibitor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005768

endosome

GO:0005886

plasma membrane

GO:0005912

adherens junction

GO:0006468

protein phosphorylation

GO:0007264

small GTPase mediated signal transduction

GO:0016310

phosphorylation

GO:0016567

protein ubiquitination

GO:0030054

cell junction

GO:0030659

cytoplasmic vesicle membrane

GO:0031410

cytoplasmic vesicle

GO:0046872

metal ion binding

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation