Gene basic information
| LiverAtlas Gene ID |
HuLG006907 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PSME3 |
|
Synonyms |
Ki|PA28Ngamma|PA28G|REGNGAMMA |
|
Gene name |
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
|
Gene Type |
protein-coding |
|
Chromosome |
17 |
|
Genomics Location |
17q21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9570
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000075 |
cell cycle checkpoint |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0000084 |
S phase of mitotic cell cycle |
|
GO:0000216 |
M/G1 transition of mitotic cell cycle |
|
GO:0000278 |
mitotic cell cycle |
|
GO:0000502 |
proteasome complex |
|
GO:0002039 |
p53 binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0006521 |
regulation of cellular amino acid metabolic process |
|
GO:0006915 |
apoptosis |
|
GO:0006977 |
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest |
|
GO:0008537 |
proteasome activator complex |
|
GO:0010950 |
positive regulation of endopeptidase activity |
|
GO:0016032 |
viral reproduction |
|
GO:0016070 |
RNA metabolic process |
|
GO:0016071 |
mRNA metabolic process |
|
GO:0031145 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0034641 |
cellular nitrogen compound metabolic process |
|
GO:0042802 |
identical protein binding |
|
GO:0042981 |
regulation of apoptosis |
|
GO:0051436 |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0051437 |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0051439 |
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0061133 |
endopeptidase activator activity |
|
GO:0061136 |
regulation of proteasomal protein catabolic process |
|
GO:0070215 |
MDM2 binding |
