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Gene basic information

LiverAtlas Gene ID

HuLG006912

Entrez Gene ID

10202

Official Gene Symbol

DHRS2

Synonyms

HEP27|SDR25C1

Gene name

dehydrogenase/reductase (SDR family) member 2

Gene Type

protein-coding

Chromosome

14

Genomics Location

14q11.2

Known cancer genes

Yes

Protein products

Dehydrogenase/reductase (SDR family) member 2, isoform CRA a

Dehydrogenase/reductase SDR family member 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:18349
Ensembl:ENSG00000100867
HPRD:07483
RefSeq Genomic nucleotide accession:AC_000057
RefSeq Genomic nucleotide gi:89161192


Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004090

carbonyl reductase (NADPH) activity

GO:0005488

binding

GO:0005634

nucleus

GO:0005635

nuclear envelope

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0008207

C21-steroid hormone metabolic process

GO:0008285

negative regulation of cell proliferation

GO:0009636

response to toxin

GO:0016491

oxidoreductase activity

GO:0034599

cellular response to oxidative stress

GO:0043011

myeloid dendritic cell differentiation

GO:0043066

negative regulation of apoptosis

GO:0055114

oxidation-reduction process