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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006925

Entrez Gene ID

10215

Official Gene Symbol

OLIG2

Synonyms

BHLHB1|OLIGO2|PRKCBP2|RACK17|bHLHe19

Gene name

oligodendrocyte lineage transcription factor 2

Gene Type

protein-coding

Chromosome

21

Genomics Location

21q22.11

Known cancer genes

Yes

Protein products

Oligodendrocyte transcription factor 2

OLIG2 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9398
MIM:606386
Ensembl:ENSG00000205927
HPRD:07334
RefSeq Genomic nucleotide accession:AC_000064
RefSeq Genomic nucleotide gi:89161201

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003705

sequence-specific enhancer binding RNA polymerase II transcription factor activity

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0006355

regulation of transcription, DNA-dependent

GO:0007275

multicellular organismal development

GO:0007399

nervous system development

GO:0021530

spinal cord oligodendrocyte cell fate specification

GO:0042552

myelination

GO:0042803

protein homodimerization activity

GO:0045665

negative regulation of neuron differentiation

GO:0048663

neuron fate commitment

GO:0048714

positive regulation of oligodendrocyte differentiation