Gene basic information
| LiverAtlas Gene ID |
HuLG006961 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SPRY2 |
|
Synonyms |
MGC23039|hSPRY2 |
|
Gene name |
sprouty homolog 2 (Drosophila) |
|
Gene Type |
protein-coding |
|
Chromosome |
13 |
|
Genomics Location |
13q31.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11270
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005856 |
cytoskeleton |
|
GO:0005874 |
microtubule |
|
GO:0005886 |
plasma membrane |
|
GO:0007173 |
epidermal growth factor receptor signaling pathway |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007605 |
sensory perception of sound |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009966 |
regulation of signal transduction |
|
GO:0010628 |
positive regulation of gene expression |
|
GO:0032587 |
ruffle membrane |
|
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
|
GO:0034261 |
negative regulation of Ras GTPase activity |
|
GO:0040037 |
negative regulation of fibroblast growth factor receptor signaling pathway |
|
GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
|
GO:0042472 |
inner ear morphogenesis |
|
GO:0042995 |
cell projection |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043407 |
negative regulation of MAP kinase activity |
|
GO:0043539 |
protein serine/threonine kinase activator activity |
|
GO:0045165 |
cell fate commitment |
|
GO:0046580 |
negative regulation of Ras protein signal transduction |
|
GO:0048754 |
branching morphogenesis of a tube |
|
GO:0051387 |
negative regulation of nerve growth factor receptor signaling pathway |
|
GO:0051897 |
positive regulation of protein kinase B signaling cascade |
|
GO:0060425 |
lung morphogenesis |
|
GO:0060437 |
lung growth |
|
GO:0070373 |
negative regulation of ERK1 and ERK2 cascade |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
|
GO:0071902 |
positive regulation of protein serine/threonine kinase activity |
