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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006965

Entrez Gene ID

10257

Official Gene Symbol

ABCC4

Synonyms

EST170205|MOATNB|MOATB|MRP4

Gene name

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

Gene Type

protein-coding

Chromosome

13

Genomics Location

13q32

Known cancer genes

Yes

Protein products

Multidrug resistance-associated protein 4

ABC transporter MOAT-B isoform

ABCC4 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:55
MIM:605250
Ensembl:ENSG00000125257
HPRD:05583
RefSeq Genomic nucleotide accession:AC_000056
RefSeq Genomic nucleotide gi:89161191

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0002576

platelet degranulation

GO:0005254

chloride channel activity

GO:0005524

ATP binding

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0006811

ion transport

GO:0007596

blood coagulation

GO:0008150

biological process

GO:0015662

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

GO:0016021

integral to membrane

GO:0016404

15-hydroxyprostaglandin dehydrogenase (NAD+) activity

GO:0016887

ATPase activity

GO:0030168

platelet activation

GO:0031088

platelet dense granule membrane

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO:0055085

transmembrane transport