HuLG007016

Entrez Gene ID

10320

Official Gene Symbol

IKZF1

Synonyms

Hs.54452|IK1|IKAROS|LYF1|PRO0758|ZNFN1A1|hIkN1

Gene name

IKAROS family zinc finger 1 (Ikaros)

Gene Type

protein-coding

Chromosome

7

Genomics Location

7p13-p11.1

Known cancer genes

Yes

Protein products

DNA-binding protein Ikaros

Zinc finger protein, subfamily 1A, 1 (Ikaros)

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:13176
MIM:603023
Ensembl:ENSG00000185811
HPRD:04318
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0001779

natural killer cell differentiation

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005721

centromeric heterochromatin

GO:0005737

cytoplasm

GO:0006355

regulation of transcription, DNA-dependent

GO:0007049

cell cycle

GO:0007275

multicellular organismal development

GO:0007498

mesoderm development

GO:0008270

zinc ion binding

GO:0016568

chromatin modification

GO:0030097

hemopoiesis

GO:0030183

B cell differentiation

GO:0030217

T cell differentiation

GO:0030900

forebrain development

GO:0040018

positive regulation of multicellular organism growth

GO:0043565

sequence-specific DNA binding

GO:0045660

positive regulation of neutrophil differentiation

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046872

metal ion binding

GO:0046982

protein heterodimerization activity

GO:0048535

lymph node development

GO:0048538

thymus development

GO:0048541

Peyer's patch development

GO:0048732

gland development

GO:0051138

positive regulation of NK T cell differentiation

GO:0060041

retina development in camera-type eye