HuLG007022

Entrez Gene ID

10327

Official Gene Symbol

AKR1A1

Synonyms

ALDR1|ALR|ARM|DD3|MGC12529|MGC1380

Gene name

aldo-keto reductase family 1, member A1 (aldehyde reductase)

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p33-p32

Protein products

Alcohol dehydrogenase [NADP+]

Related liver disease name

Liver fibrosis and liver cirrhosis

Viral hepatitis

Drug-induced hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:380
MIM:103830
Ensembl:ENSG00000117448
HPRD:00069
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0004032

alditol:NADP+ 1-oxidoreductase activity

GO:0005515

protein binding

GO:0005829

cytosol

GO:0006006

glucose metabolic process

GO:0006081

cellular aldehyde metabolic process

GO:0009055

electron carrier activity

GO:0016324

apical plasma membrane

GO:0016491

oxidoreductase activity

GO:0019853

L-ascorbic acid biosynthetic process

GO:0042840

D-glucuronate catabolic process

GO:0046185

aldehyde catabolic process

GO:0047939

L-glucuronate reductase activity