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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG007049

Entrez Gene ID

10370

Official Gene Symbol

CITED2

Synonyms

MRG1|P35SRJ

Gene name

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q23.3

Known cancer genes

Yes

Protein products

Cbp/p300-interacting transactivator 2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1987
MIM:602937
Ensembl:ENSG00000164442
HPRD:04245
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0000790

nuclear chromatin

GO:0001568

blood vessel development

GO:0001570

vasculogenesis

GO:0001666

response to hypoxia

GO:0001829

trophectodermal cell differentiation

GO:0001889

liver development

GO:0001892

embryonic placenta development

GO:0003156

regulation of organ formation

GO:0003682

chromatin binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003713

transcription coactivator activity

GO:0003714

transcription corepressor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0006351

transcription, DNA-dependent

GO:0006916

anti-apoptosis

GO:0007368

determination of left/right symmetry

GO:0007417

central nervous system development

GO:0007507

heart development

GO:0007530

sex determination

GO:0008283

cell proliferation

GO:0010628

positive regulation of gene expression

GO:0010629

negative regulation of gene expression

GO:0022409

positive regulation of cell-cell adhesion

GO:0030325

adrenal gland development

GO:0030336

negative regulation of cell migration

GO:0030511

positive regulation of transforming growth factor beta receptor signaling pathway

GO:0034405

response to fluid shear stress

GO:0035360

positive regulation of peroxisome proliferator activated receptor signaling pathway

GO:0043627

response to estrogen stimulus

GO:0045787

positive regulation of cell cycle

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046697

decidualization

GO:0050693

LBD domain binding

GO:0060136

embryonic process involved in female pregnancy

GO:2000020

positive regulation of male gonad development