Gene basic information
| LiverAtlas Gene ID |
HuLG007063 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
NOD1 |
|
Synonyms |
CARD4|CLR7.1|NLRC1 |
|
Gene name |
nucleotide-binding oligomerization domain containing 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
7 |
|
Genomics Location |
7p15-p14 |
|
Known cancer genes |
Yes |
|
Protein products |
Nucleotide-binding oligomerization domain-containing protein 1 |
|
Database cross reference |
HGNC:16390
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0002224 |
toll-like receptor signaling pathway |
|
GO:0002606 |
positive regulation of dendritic cell antigen processing and presentation |
|
GO:0002755 |
MyD88-dependent toll-like receptor signaling pathway |
|
GO:0002756 |
MyD88-independent toll-like receptor signaling pathway |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006915 |
apoptosis |
|
GO:0006917 |
induction of apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0006952 |
defense response |
|
GO:0006954 |
inflammatory response |
|
GO:0007165 |
signal transduction |
|
GO:0007254 |
JNK cascade |
|
GO:0008063 |
Toll signaling pathway |
|
GO:0008656 |
caspase activator activity |
|
GO:0009595 |
detection of biotic stimulus |
|
GO:0016045 |
detection of bacterium |
|
GO:0016323 |
basolateral plasma membrane |
|
GO:0032755 |
positive regulation of interleukin-6 production |
|
GO:0032760 |
positive regulation of tumor necrosis factor production |
|
GO:0032874 |
positive regulation of stress-activated MAPK cascade |
|
GO:0034130 |
toll-like receptor 1 signaling pathway |
|
GO:0034134 |
toll-like receptor 2 signaling pathway |
|
GO:0034138 |
toll-like receptor 3 signaling pathway |
|
GO:0034142 |
toll-like receptor 4 signaling pathway |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0042228 |
interleukin-8 biosynthetic process |
|
GO:0042742 |
defense response to bacterium |
|
GO:0042802 |
identical protein binding |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0042834 |
peptidoglycan binding |
|
GO:0042981 |
regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0045087 |
innate immune response |
|
GO:0046330 |
positive regulation of JNK cascade |
|
GO:0050700 |
CARD domain binding |
|
GO:0050830 |
defense response to Gram-positive bacterium |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051259 |
protein oligomerization |
|
GO:0051403 |
stress-activated MAPK cascade |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
