HuLG007067

Entrez Gene ID

10396

Official Gene Symbol

ATP8A1

Synonyms

ATPASEII|ATPIA|ATPP2|MGC130042|MGC130043|MGC26327

Gene name

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

Gene Type

protein-coding

Chromosome

4

Genomics Location

4p13

Known cancer genes

Yes

Protein products

Probable phospholipid-transporting ATPase IA

Uncharacterized protein

ATP8A1 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:13531
MIM:609542
Ensembl:ENSG00000124406
HPRD:16527
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000166

nucleotide binding

GO:0000287

magnesium ion binding

GO:0004012

phospholipid-translocating ATPase activity

GO:0005524

ATP binding

GO:0005886

plasma membrane

GO:0006754

ATP biosynthetic process

GO:0015247

aminophospholipid transporter activity

GO:0015662

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

GO:0015914

phospholipid transport

GO:0015917

aminophospholipid transport

GO:0016021

integral to membrane

GO:0016787

hydrolase activity

GO:0019829

cation-transporting ATPase activity

GO:0031410

cytoplasmic vesicle

GO:0034220

ion transmembrane transport

GO:0042584

chromaffin granule membrane

GO:0055085

transmembrane transport