HuLG007086

Entrez Gene ID

10419

Official Gene Symbol

PRMT5

Synonyms

HRMT1L5|IBP72|JBP1|SKB1|SKB1Hs

Gene name

protein arginine methyltransferase 5

Gene Type

protein-coding

Chromosome

14

Genomics Location

14q11.2

Known cancer genes

Yes

Protein products

Protein arginine methyltransferase 5, isoform CRA d

Protein arginine N-methyltransferase 5

Database cross reference

HGNC:10894
MIM:604045
Ensembl:ENSG00000100462
HPRD:04955
RefSeq Genomic nucleotide accession:AC_000057
RefSeq Genomic nucleotide gi:89161192

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0000387

spliceosomal snRNP assembly

GO:0003682

chromatin binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006355

regulation of transcription, DNA-dependent

GO:0007088

regulation of mitosis

GO:0008168

methyltransferase activity

GO:0008283

cell proliferation

GO:0008469

histone-arginine N-methyltransferase activity

GO:0016070

RNA metabolic process

GO:0016568

chromatin modification

GO:0016740

transferase activity

GO:0018216

peptidyl-arginine methylation

GO:0019918

peptidyl-arginine methylation, to symmetrical-dimethyl arginine

GO:0034660

ncRNA metabolic process

GO:0035243

protein-arginine omega-N symmetric methyltransferase activity

GO:0035246

peptidyl-arginine N-methylation

GO:0043021

ribonucleoprotein binding

GO:0043985

histone H4-R3 methylation