Gene basic information
| LiverAtlas Gene ID |
HuLG007208 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ARFGEF2 |
|
Synonyms |
BIG2|FLJ23723|PVNH2|dJ1164I10.1 |
|
Gene name |
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
|
Gene Type |
protein-coding |
|
Chromosome |
20 |
|
Genomics Location |
20q13.13 |
|
Known cancer genes |
Yes |
|
Protein products |
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 variant |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:15853
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000139 |
Golgi membrane |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005086 |
ARF guanyl-nucleotide exchange factor activity |
|
GO:0005488 |
binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005802 |
trans-Golgi network |
|
GO:0005829 |
cytosol |
|
GO:0006887 |
exocytosis |
|
GO:0016020 |
membrane |
|
GO:0016192 |
vesicle-mediated transport |
|
GO:0017022 |
myosin binding |
|
GO:0032012 |
regulation of ARF protein signal transduction |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0050811 |
GABA receptor binding |
