HuLG007209

Entrez Gene ID

10565

Official Gene Symbol

ARFGEF1

Synonyms

ARFGEP1|BIG1|D730028O18Rik|DKFZP434L057|P200

Gene name

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

Gene Type

protein-coding

Chromosome

8

Genomics Location

8q13

Known cancer genes

Yes

Protein products

cDNA FLJ12495 fis, clone NT2RM2001652, highly similar to Brefeldin A-inhibited guanine nucleotide-exchange protein 1

Brefeldin A-inhibited guanine nucleotide-exchange protein 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:15772
MIM:604141
Ensembl:ENSG00000066777
HPRD:09163
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005086

ARF guanyl-nucleotide exchange factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0006887

exocytosis

GO:0008060

ARF GTPase activator activity

GO:0017022

myosin binding

GO:0032012

regulation of ARF protein signal transduction