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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG007534

Entrez Gene ID

10993

Official Gene Symbol

SDS

Synonyms

SDH

Gene name

serine dehydratase

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.13

Known cancer genes

Yes

Protein products

SDS protein

L-serine dehydratase/L-threonine deaminase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:10691
MIM:182128
Ensembl:ENSG00000135094
HPRD:01633
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003941

L-serine ammonia-lyase activity

GO:0004794

L-threonine ammonia-lyase activity

GO:0005575

cellular component

GO:0005737

cytoplasm

GO:0006094

gluconeogenesis

GO:0006520

cellular amino acid metabolic process

GO:0006565

L-serine catabolic process

GO:0016829

lyase activity

GO:0030170

pyridoxal phosphate binding

GO:0031667

response to nutrient levels

GO:0033590

response to cobalamin

GO:0042803

protein homodimerization activity

GO:0042866

pyruvate biosynthetic process

GO:0043200

response to amino acid stimulus