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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG007591

Entrez Gene ID

11065

Official Gene Symbol

UBE2C

Synonyms

UBCH10|dJ447F3.2

Gene name

ubiquitin-conjugating enzyme E2C

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q13.12

Known cancer genes

Yes

Protein products

Ubiquitin-conjugating enzyme E2C, isoform CRA d

Ubiquitin carrier protein

Ubiquitin carrier protein

Ubiquitin carrier protein

Ubiquitin-conjugating enzyme E2 C

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:15937
MIM:605574
Ensembl:ENSG00000175063
HPRD:05717
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000166

nucleotide binding

GO:0000278

mitotic cell cycle

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005654

nucleoplasm

GO:0005680

anaphase-promoting complex

GO:0005829

cytosol

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0007049

cell cycle

GO:0007051

spindle organization

GO:0007067

mitosis

GO:0007094

mitotic cell cycle spindle assembly checkpoint

GO:0008054

cyclin catabolic process

GO:0010458

exit from mitosis

GO:0010994

free ubiquitin chain polymerization

GO:0016567

protein ubiquitination

GO:0016874

ligase activity

GO:0016881

acid-amino acid ligase activity

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0031536

positive regulation of exit from mitosis

GO:0048015

phosphatidylinositol-mediated signaling

GO:0051301

cell division

GO:0051436

negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051437

positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051439

regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051488

activation of anaphase-promoting complex activity

GO:0070936

protein K48-linked ubiquitination

GO:0070979

protein K11-linked ubiquitination