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Gene basic information

LiverAtlas Gene ID

HuLG007595

Entrez Gene ID

11069

Official Gene Symbol

RAPGEF4

Synonyms

CAMPNGEFII|CGEF2|EPAC2|Nbla00496

Gene name

Rap guanine nucleotide exchange factor (GEF) 4

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q31-q32

Known cancer genes

Yes

Protein products

Putative uncharacterized protein Nbla00496

Rap guanine nucleotide exchange factor 4

Database cross reference

HGNC:16626
MIM:606058
Ensembl:ENSG00000091428
HPRD:06929
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001932

regulation of protein phosphorylation

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005088

Ras guanyl-nucleotide exchange factor activity

GO:0005622

intracellular

GO:0005624

membrane fraction

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0005952

cAMP-dependent protein kinase complex

GO:0006112

energy reserve metabolic process

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007596

blood coagulation

GO:0008603

cAMP-dependent protein kinase regulator activity

GO:0017016

Ras GTPase binding

GO:0017156

calcium ion-dependent exocytosis

GO:0017157

regulation of exocytosis

GO:0019933

cAMP-mediated signaling

GO:0030552

cAMP binding

GO:0050796

regulation of insulin secretion

GO:0051056

regulation of small GTPase mediated signal transduction