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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG007598

Entrez Gene ID

11073

Official Gene Symbol

TOPBP1

Synonyms

TOP2BP1

Gene name

topoisomerase (DNA) II binding protein 1

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q22.1

Known cancer genes

Yes

Protein products

Topoisomerase (DNA) II binding protein 1

Topoisomerase (DNA) II binding protein 1

TOPBP1 protein

DNA topoisomerase 2-binding protein 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:17008
MIM:607760
Ensembl:ENSG00000163781
HPRD:09678
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000794

condensed nuclear chromosome

GO:0000922

spindle pole

GO:0001673

male germ cell nucleus

GO:0003677

DNA binding

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005694

chromosome

GO:0005737

cytoplasm

GO:0005815

microtubule organizing center

GO:0005856

cytoskeleton

GO:0006259

DNA metabolic process

GO:0006281

DNA repair

GO:0006974

response to DNA damage stimulus

GO:0008022

protein C-terminus binding

GO:0010212

response to ionizing radiation

GO:0016605

PML body