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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG007712

Entrez Gene ID

11214

Official Gene Symbol

AKAP13

Synonyms

AKAPNLbc|ARHGEF13|BRX|FLJ11952|FLJ43341|HAN3|Ht31|LBC|PROTONLB|PROTONLBC|cNlbc

Gene name

A kinase (PRKA) anchor protein 13

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q24-q25

Known cancer genes

Yes

Protein products

A kinase (PRKA) anchor protein 13, isoform CRA a

A-kinase anchor protein 13

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:371
MIM:604686
Ensembl:ENSG00000170776
HPRD:05253
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004691

cAMP-dependent protein kinase activity

GO:0004871

signal transducer activity

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005089

Rho guanyl-nucleotide exchange factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005624

membrane fraction

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006915

apoptosis

GO:0007264

small GTPase mediated signal transduction

GO:0008624

induction of apoptosis by extracellular signals

GO:0016020

membrane

GO:0035023

regulation of Rho protein signal transduction

GO:0046872

metal ion binding

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051056

regulation of small GTPase mediated signal transduction