Gene basic information
| LiverAtlas Gene ID |
HuLG007917 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
DKK1 |
|
Synonyms |
DKKN1|SK |
|
Gene name |
dickkopf homolog 1 (Xenopus laevis) |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10q11.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2891
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0000904 |
cell morphogenesis involved in differentiation |
|
GO:0002090 |
regulation of receptor internalization |
|
GO:0004871 |
signal transducer activity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005886 |
plasma membrane |
|
GO:0007165 |
signal transduction |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007492 |
endoderm development |
|
GO:0008083 |
growth factor activity |
|
GO:0030326 |
embryonic limb morphogenesis |
|
GO:0030514 |
negative regulation of BMP signaling pathway |
|
GO:0030900 |
forebrain development |
|
GO:0031333 |
negative regulation of protein complex assembly |
|
GO:0032526 |
response to retinoic acid |
|
GO:0033137 |
negative regulation of peptidyl-serine phosphorylation |
|
GO:0048019 |
receptor antagonist activity |
|
GO:0050750 |
low-density lipoprotein particle receptor binding |
|
GO:0060325 |
face morphogenesis |
|
GO:0090082 |
positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway |
|
GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
|
GO:0090244 |
Wnt receptor signaling pathway involved in somitogenesis |
