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Gene basic information

LiverAtlas Gene ID

HuLG007965

Entrez Gene ID

23028

Official Gene Symbol

KDM1A

Synonyms

AOF2|BHC110|KDM1|KIAA0601|LSD1

Gene name

lysine (K)-specific demethylase 1A

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36.12

Known cancer genes

Yes

Protein products

Lysine-specific histone demethylase 1A

Database cross reference

HGNC:29079
MIM:609132
Ensembl:ENSG00000004487
HPRD:09800
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0000790

nuclear chromatin

GO:0001701

in utero embryonic development

GO:0002039

p53 binding

GO:0003682

chromatin binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005667

transcription factor complex

GO:0006355

regulation of transcription, DNA-dependent

GO:0006482

protein demethylation

GO:0007275

multicellular organismal development

GO:0007596

blood coagulation

GO:0008134

transcription factor binding

GO:0008283

cell proliferation

GO:0016491

oxidoreductase activity

GO:0016568

chromatin modification

GO:0019899

enzyme binding

GO:0021983

pituitary gland development

GO:0030374

ligand-dependent nuclear receptor transcription coactivator activity

GO:0032091

negative regulation of protein binding

GO:0032451

demethylase activity

GO:0032452

histone demethylase activity

GO:0032453

histone demethylase activity (H3-K4 specific)

GO:0032454

histone demethylase activity (H3-K9 specific)

GO:0033169

histone H3-K9 demethylation

GO:0034339

regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

GO:0034648

histone demethylase activity (H3-dimethyl-K4 specific)

GO:0034720

histone H3-K4 demethylation

GO:0043066

negative regulation of apoptosis

GO:0043392

negative regulation of DNA binding

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046886

positive regulation of hormone biosynthetic process

GO:0050660

flavin adenine dinucleotide binding

GO:0050681

androgen receptor binding

GO:0051091

positive regulation of sequence-specific DNA binding transcription factor activity

GO:0051577

MyoD binding

GO:0055001

muscle cell development

GO:0055114

oxidation-reduction process