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Gene basic information

LiverAtlas Gene ID

HuLG008181

Entrez Gene ID

23293

Official Gene Symbol

SMG6

Synonyms

C17orf31|EST1A|KIAA0732|SMGN6

Gene name

Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p13.3

Known cancer genes

Yes

Protein products

Telomerase-binding protein EST1A

Database cross reference

HGNC:17809
MIM:610963
Ensembl:ENSG00000070366
HPRD:06502
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

 

Ontology annotation

GO ID

GO annotation

GO:0000184

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

GO:0000723

telomere maintenance

GO:0000781

chromosome, telomeric region

GO:0003677

DNA binding

GO:0004521

endoribonuclease activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005694

chromosome

GO:0005697

telomerase holoenzyme complex

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006406

mRNA export from nucleus

GO:0016787

hydrolase activity

GO:0035303

regulation of dephosphorylation

GO:0042162

telomeric DNA binding

GO:0046872

metal ion binding