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Gene basic information

LiverAtlas Gene ID

HuLG008242

Entrez Gene ID

23370

Official Gene Symbol

ARHGEF18

Synonyms

KIAA0521|MGC15913|P114NRhoGEF

Gene name

Rho/Rac guanine nucleotide exchange factor (GEF) 18

Gene Type

protein-coding

Chromosome

19

Genomics Location

19p13.3

Known cancer genes

Yes

Protein products

Rho guanine nucleotide exchange factor 18

Database cross reference

HGNC:17090
Ensembl:ENSG00000104880
HPRD:12479
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197


 

Ontology annotation

GO ID

GO annotation

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005089

Rho guanyl-nucleotide exchange factor activity

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006915

apoptosis

GO:0007264

small GTPase mediated signal transduction

GO:0008360

regulation of cell shape

GO:0008624

induction of apoptosis by extracellular signals

GO:0030036

actin cytoskeleton organization

GO:0035023

regulation of Rho protein signal transduction

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051056

regulation of small GTPase mediated signal transduction