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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG008268

Entrez Gene ID

23404

Official Gene Symbol

EXOSC2

Synonyms

RRP4|Rrp4p|hRrp4p|p7

Gene name

exosome component 2

Gene Type

protein-coding

Chromosome

9

Genomics Location

9q34

Known cancer genes

Yes

Protein products

EXOSC2 protein

Exosome component 2

Exosome complex component RRP4

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:17097
MIM:602238
Ensembl:ENSG00000130713
HPRD:03758
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000175

3'-5'-exoribonuclease activity

GO:0000178

exosome (RNase complex)

GO:0000288

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

GO:0004532

exoribonuclease activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006364

rRNA processing

GO:0008312

7S RNA binding

GO:0016070

RNA metabolic process

GO:0016071

mRNA metabolic process

GO:0030307

positive regulation of cell growth

GO:0043928

exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay