HuLG008272

Entrez Gene ID

23409

Official Gene Symbol

SIRT4

Synonyms

MGC130046|MGC130047|MGC57437|SIR2L4

Gene name

sirtuin 4

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q

Protein products

NAD-dependent ADP-ribosyltransferase sirtuin-4

Database cross reference

HGNC:14932
MIM:604482
Ensembl:ENSG00000089163
HPRD:06837
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

GO annotation

GO:0003950

NAD+ ADP-ribosyltransferase activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0006342

chromatin silencing

GO:0006355

regulation of transcription, DNA-dependent

GO:0006471

protein ADP-ribosylation

GO:0006476

protein deacetylation

GO:0008270

zinc ion binding

GO:0016740

transferase activity

GO:0016811

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

GO:0034979

NAD-dependent protein deacetylase activity

GO:0046676

negative regulation of insulin secretion

GO:0046872

metal ion binding

GO:0070403

NAD+ binding