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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG008487

Entrez Gene ID

23779

Official Gene Symbol

ARHGAP8

Synonyms

BPGAP1|FLJ20185|PP610

Gene name

Rho GTPase activating protein 8

Gene Type

protein-coding

Chromosome

22

Genomics Location

22q13.31

Protein products

Rho GTPase activating protein 8

ARHGAP8 protein

Rho GTPase-activating protein 8

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:677
MIM:609405
Ensembl:ENSG00000241484
Ensembl:ENSG00000248405
HPRD:06448
RefSeq Genomic nucleotide accession:AC_000065
RefSeq Genomic nucleotide gi:89161202

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005096

GTPase activator activity

GO:0005100

Rho GTPase activator activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005829

cytosol

GO:0007165

signal transduction

GO:0007264

small GTPase mediated signal transduction

GO:0032321

positive regulation of Rho GTPase activity

GO:0043547

positive regulation of GTPase activity

GO:0051056

regulation of small GTPase mediated signal transduction

GO:0070374

positive regulation of ERK1 and ERK2 cascade