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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG008928

Entrez Gene ID

26986

Official Gene Symbol

PABPC1

Synonyms

PAB1|PABP|PABP1|PABPC2|PABPL1

Gene name

poly(A) binding protein, cytoplasmic 1

Gene Type

protein-coding

Chromosome

8

Genomics Location

8q22.2-q23

Protein products

Polyadenylate-binding protein 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:8554
MIM:604679
Ensembl:ENSG00000070756
HPRD:05247
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000288

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

GO:0000289

nuclear-transcribed mRNA poly(A) tail shortening

GO:0000398

nuclear mRNA splicing, via spliceosome

GO:0003723

RNA binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006378

mRNA polyadenylation

GO:0006412

translation

GO:0008022

protein C-terminus binding

GO:0008143

poly(A) RNA binding

GO:0008380

RNA splicing

GO:0008494

translation activator activity

GO:0010467

gene expression

GO:0016070

RNA metabolic process

GO:0016071

mRNA metabolic process

GO:0030529

ribonucleoprotein complex

GO:0044267

cellular protein metabolic process

GO:0045727

positive regulation of translation

GO:0048255

mRNA stabilization

GO:0071013

catalytic step 2 spliceosome

GO:2000623

negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay