Gene basic information
LiverAtlas Gene ID |
HuLG008928 |
Entrez Gene ID |
|
Official Gene Symbol |
PABPC1 |
Synonyms |
PAB1|PABP|PABP1|PABPC2|PABPL1 |
Gene name |
poly(A) binding protein, cytoplasmic 1 |
Gene Type |
protein-coding |
Chromosome |
8 |
Genomics Location |
8q22.2-q23 |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:8554
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0000288 |
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
GO:0000289 |
nuclear-transcribed mRNA poly(A) tail shortening |
GO:0000398 |
nuclear mRNA splicing, via spliceosome |
GO:0003723 |
RNA binding |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005737 |
cytoplasm |
GO:0005829 |
cytosol |
GO:0006378 |
mRNA polyadenylation |
GO:0006412 |
translation |
GO:0008022 |
protein C-terminus binding |
GO:0008143 |
poly(A) RNA binding |
GO:0008380 |
RNA splicing |
GO:0008494 |
translation activator activity |
GO:0010467 |
gene expression |
GO:0016070 |
RNA metabolic process |
GO:0016071 |
mRNA metabolic process |
GO:0030529 |
ribonucleoprotein complex |
GO:0044267 |
cellular protein metabolic process |
GO:0045727 |
positive regulation of translation |
GO:0048255 |
mRNA stabilization |
GO:0071013 |
catalytic step 2 spliceosome |
GO:2000623 |
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |