Gene basic information
| LiverAtlas Gene ID |
HuLG008989 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
BBC3 |
|
Synonyms |
FLJ42994|JFY1|PUMA |
|
Gene name |
BCL2 binding component 3 |
|
Gene Type |
protein-coding |
|
Chromosome |
19 |
|
Genomics Location |
19q13.3-q13.4 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:17868
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001836 |
release of cytochrome c from mitochondria |
|
GO:0001844 |
protein insertion into mitochondrial membrane involved in induction of apoptosis |
|
GO:0005515 |
protein binding |
|
GO:0005739 |
mitochondrion |
|
GO:0005741 |
mitochondrial outer membrane |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0006917 |
induction of apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0008340 |
determination of adult lifespan |
|
GO:0008629 |
induction of apoptosis by intracellular signals |
|
GO:0008633 |
activation of pro-apoptotic gene products |
|
GO:0032464 |
positive regulation of protein homooligomerization |
|
GO:0032471 |
reduction of endoplasmic reticulum calcium ion concentration |
|
GO:0042771 |
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis |
|
GO:0045926 |
negative regulation of growth |
|
GO:0051209 |
release of sequestered calcium ion into cytosol |
|
GO:0070245 |
positive regulation of thymocyte apoptosis |
|
GO:0071456 |
cellular response to hypoxia |
|
GO:0090200 |
positive regulation of release of cytochrome c from mitochondria |
