Gene basic information
| LiverAtlas Gene ID |
HuLG009019 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
EIF2C2 |
|
Synonyms |
AGO2|MGC3183|Q10 |
|
Gene name |
eukaryotic translation initiation factor 2C, 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8q24 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3263
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000340 |
RNA 7-methylguanosine cap binding |
|
GO:0000932 |
cytoplasmic mRNA processing body |
|
GO:0003743 |
translation initiation factor activity |
|
GO:0004519 |
endonuclease activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005845 |
mRNA cap binding complex |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006412 |
translation |
|
GO:0006413 |
translational initiation |
|
GO:0006417 |
regulation of translation |
|
GO:0016442 |
RNA-induced silencing complex |
|
GO:0016787 |
hydrolase activity |
|
GO:0031047 |
gene silencing by RNA |
|
GO:0031054 |
pre-microRNA processing |
|
GO:0035068 |
micro-ribonucleoprotein complex |
|
GO:0035197 |
siRNA binding |
|
GO:0035278 |
negative regulation of translation involved in gene silencing by miRNA |
|
GO:0035279 |
mRNA cleavage involved in gene silencing by miRNA |
|
GO:0045947 |
negative regulation of translational initiation |
|
GO:0046872 |
metal ion binding |
|
GO:0070551 |
endoribonuclease activity, cleaving siRNA-paired mRNA |
