Gene basic information
| LiverAtlas Gene ID |
HuLG009045 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ARHGEF16 |
|
Synonyms |
GEF16|NBR |
|
Gene name |
Rho guanine nucleotide exchange factor (GEF) 16 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p36.3 |
|
Known cancer genes |
Yes |
|
Protein products |
Rho guanine nucleotide exchange factor 16 cDNA FLJ38665 fis, clone HLUNG2003378, highly similar to Rho guanine nucleotide exchange factor 16 |
|
Database cross reference |
HGNC:15515
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0017048 |
Rho GTPase binding |
|
GO:0030165 |
PDZ domain binding |
|
GO:0030971 |
receptor tyrosine kinase binding |
|
GO:0032863 |
activation of Rac GTPase activity |
|
GO:0032864 |
activation of Cdc42 GTPase activity |
|
GO:0035023 |
regulation of Rho protein signal transduction |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0051056 |
regulation of small GTPase mediated signal transduction |
|
GO:0060326 |
cell chemotaxis |
|
GO:0090004 |
positive regulation of establishment of protein localization in plasma membrane |
