HuLG009058

Entrez Gene ID

27250

Official Gene Symbol

PDCD4

Synonyms

H731|MGC33046|MGC33047

Gene name

programmed cell death 4 (neoplastic transformation inhibitor)

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q24

Known cancer genes

Yes

Protein products

cDNA, FLJ96314, highly similar to Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript

cDNA FLJ58014, highly similar to Homo sapiens programmed cell death 4, transcript variant 1, mRNA

Uncharacterized protein

Programmed cell death protein 4

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:8763
MIM:608610
Ensembl:ENSG00000150593
HPRD:10549
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

GO annotation

GO:0003723

RNA binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006915

apoptosis

GO:0007569

cell aging

GO:0043508

negative regulation of JUN kinase activity

GO:0045786

negative regulation of cell cycle

GO:0045892

negative regulation of transcription, DNA-dependent