HuLG009303

Entrez Gene ID

29927

Official Gene Symbol

SEC61A1

Synonyms

HSEC61|SEC61|SEC61A

Gene name

Sec61 alpha 1 subunit (S. cerevisiae)

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q21.3

Known cancer genes

Yes

Protein products

cDNA FLJ10827 fis, clone NT2RP4001117, highly similar to Protein transport protein Sec61 subunit alpha isoform 1

Sec61 alpha 1 subunit (S. cerevisiae), isoform CRA c

Protein transport protein Sec61 subunit alpha isoform 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:18276
MIM:609213
Ensembl:ENSG00000058262
HPRD:15316
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0005515

protein binding

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0015031

protein transport

GO:0015450

P-P-bond-hydrolysis-driven protein transmembrane transporter activity

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0019718

rough microsome

GO:0030176

integral to endoplasmic reticulum membrane

GO:0034341

response to interferon-gamma

GO:0043022

ribosome binding

GO:0045047

protein targeting to ER

GO:0055085

transmembrane transport