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Gene basic information

LiverAtlas Gene ID

HuLG009395

Entrez Gene ID

50484

Official Gene Symbol

RRM2B

Synonyms

DKFZp686M05248|MGC102856|MGC42116|MTDPS8A|MTDPS8B|P53R2

Gene name

ribonucleotide reductase M2 B (TP53 inducible)

Gene Type

protein-coding

Chromosome

8

Genomics Location

8q23.1

Known cancer genes

Yes

Protein products

Ribonucleotide reductase M2 B (TP53 inducible), isoform CRA c

Putative uncharacterized protein DKFZp686M05248

Ribonucleoside-diphosphate reductase subunit M2 B

Database cross reference

HGNC:17296
MIM:604712
Ensembl:ENSG00000048392
HPRD:05276
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

 

Ontology annotation

GO ID

GO annotation

GO:0001822

kidney development

GO:0003014

renal system process

GO:0004748

ribonucleoside-diphosphate reductase activity

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0006260

DNA replication

GO:0006264

mitochondrial DNA replication

GO:0006281

DNA repair

GO:0006917

induction of apoptosis

GO:0006979

response to oxidative stress

GO:0009186

deoxyribonucleoside diphosphate metabolic process

GO:0009200

deoxyribonucleoside triphosphate metabolic process

GO:0009263

deoxyribonucleotide biosynthetic process

GO:0015949

nucleobase, nucleoside and nucleotide interconversion

GO:0016491

oxidoreductase activity

GO:0046914

transition metal ion binding

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process