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Gene basic information

LiverAtlas Gene ID

HuLG009401

Entrez Gene ID

50506

Official Gene Symbol

DUOX2

Synonyms

LNOX2|NOXEF2|P138NTOX|TDH6|THOX2

Gene name

dual oxidase 2

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q15.3

Known cancer genes

Yes

Protein products

DUOX2

Dual oxidase 2

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:13273
MIM:606759
Ensembl:ENSG00000140279
HPRD:05997
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

 

Ontology annotation

GO ID

GO annotation

GO:0004601

peroxidase activity

GO:0005509

calcium ion binding

GO:0005886

plasma membrane

GO:0006979

response to oxidative stress

GO:0009055

electron carrier activity

GO:0009566

fertilization

GO:0009615

response to virus

GO:0016021

integral to membrane

GO:0016174

NAD(P)H oxidase activity

GO:0016324

apical plasma membrane

GO:0016491

oxidoreductase activity

GO:0019221

cytokine-mediated signaling pathway

GO:0020037

heme binding

GO:0030282

bone mineralization

GO:0030878

thyroid gland development

GO:0035264

multicellular organism growth

GO:0042335

cuticle development

GO:0042403

thyroid hormone metabolic process

GO:0042446

hormone biosynthetic process

GO:0042744

hydrogen peroxide catabolic process

GO:0048839

inner ear development

GO:0048855

adenohypophysis morphogenesis

GO:0050660

flavin adenine dinucleotide binding

GO:0051591

response to cAMP

GO:0055114

oxidation-reduction process