Gene basic information
| LiverAtlas Gene ID |
HuLG009402 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
NOX4 |
|
Synonyms |
KOX|KOXN1|RENOX |
|
Gene name |
NADPH oxidase 4 |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q14.2-q21 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ32627 fis, clone SYNOV1000049, highly similar to NADPH oxidase 4 (EC 1.6.3.-) cDNA FLJ56218, highly similar to NADPH oxidase 4 (EC 1.6.3.-) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:7891
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000902 |
cell morphogenesis |
|
GO:0005634 |
nucleus |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005886 |
plasma membrane |
|
GO:0005925 |
focal adhesion |
|
GO:0006954 |
inflammatory response |
|
GO:0007569 |
cell aging |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009055 |
electron carrier activity |
|
GO:0016021 |
integral to membrane |
|
GO:0016174 |
NAD(P)H oxidase activity |
|
GO:0016175 |
superoxide-generating NADPH oxidase activity |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0019826 |
oxygen sensor activity |
|
GO:0020037 |
heme binding |
|
GO:0030054 |
cell junction |
|
GO:0035051 |
cardiac cell differentiation |
|
GO:0042554 |
superoxide anion generation |
|
GO:0045453 |
bone resorption |
|
GO:0050660 |
flavin adenine dinucleotide binding |
|
GO:0055114 |
oxidation-reduction process |
|
GO:0072593 |
reactive oxygen species metabolic process |
