Gene basic information
| LiverAtlas Gene ID |
HuLG009423 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ARHGEF3 |
|
Synonyms |
DKFZp434F2429|FLJ98126|GEF3|MGC118905|STA3|XPLN |
|
Gene name |
Rho guanine nucleotide exchange factor (GEF) 3 |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p21-p13 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:683
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0007266 |
Rho protein signal transduction |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0035023 |
regulation of Rho protein signal transduction |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0051056 |
regulation of small GTPase mediated signal transduction |
