Gene basic information
LiverAtlas Gene ID |
HuLG009461 |
Entrez Gene ID |
|
Official Gene Symbol |
FOXP3 |
Synonyms |
AIID|DIETER|IPEX|MGC141961|MGC141963|PIDX|XPID |
Gene name |
forkhead box P3 |
Gene Type |
protein-coding |
Chromosome |
0 |
Genomics Location |
Xp11.23 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:6106
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
GO:0001782 |
B cell homeostasis |
GO:0001816 |
cytokine production |
GO:0002053 |
positive regulation of mesenchymal cell proliferation |
GO:0002262 |
myeloid cell homeostasis |
GO:0002456 |
T cell mediated immunity |
GO:0002513 |
tolerance induction to self antigen |
GO:0002637 |
regulation of immunoglobulin production |
GO:0002669 |
positive regulation of T cell anergy |
GO:0002677 |
negative regulation of chronic inflammatory response |
GO:0002725 |
negative regulation of T cell cytokine production |
GO:0002851 |
positive regulation of peripheral T cell tolerance induction |
GO:0003682 |
chromatin binding |
GO:0003690 |
double-stranded DNA binding |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
GO:0003705 |
sequence-specific enhancer binding RNA polymerase II transcription factor activity |
GO:0003714 |
transcription corepressor activity |
GO:0005515 |
protein binding |
GO:0005622 |
intracellular |
GO:0005634 |
nucleus |
GO:0005667 |
transcription factor complex |
GO:0005737 |
cytoplasm |
GO:0006338 |
chromatin remodeling |
GO:0006351 |
transcription, DNA-dependent |
GO:0006355 |
regulation of transcription, DNA-dependent |
GO:0007389 |
pattern specification process |
GO:0007519 |
skeletal muscle tissue development |
GO:0008270 |
zinc ion binding |
GO:0008285 |
negative regulation of cell proliferation |
GO:0008301 |
DNA bending activity |
GO:0009615 |
response to virus |
GO:0009790 |
embryo development |
GO:0009791 |
post-embryonic development |
GO:0021549 |
cerebellum development |
GO:0021757 |
caudate nucleus development |
GO:0021758 |
putamen development |
GO:0021987 |
cerebral cortex development |
GO:0031064 |
negative regulation of histone deacetylation |
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
GO:0032689 |
negative regulation of interferon-gamma production |
GO:0032693 |
negative regulation of interleukin-10 production |
GO:0032703 |
negative regulation of interleukin-2 production |
GO:0032713 |
negative regulation of interleukin-4 production |
GO:0032714 |
negative regulation of interleukin-5 production |
GO:0032715 |
negative regulation of interleukin-6 production |
GO:0032720 |
negative regulation of tumor necrosis factor production |
GO:0032792 |
negative regulation of CREB transcription factor activity |
GO:0032831 |
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation |
GO:0032914 |
positive regulation of transforming growth factor-beta1 production |
GO:0033092 |
positive regulation of immature T cell proliferation in thymus |
GO:0035035 |
histone acetyltransferase binding |
GO:0035066 |
positive regulation of histone acetylation |
GO:0035067 |
negative regulation of histone acetylation |
GO:0040007 |
growth |
GO:0042036 |
negative regulation of cytokine biosynthetic process |
GO:0042110 |
T cell activation |
GO:0042130 |
negative regulation of T cell proliferation |
GO:0042297 |
vocal learning |
GO:0042803 |
protein homodimerization activity |
GO:0042826 |
histone deacetylase binding |
GO:0043010 |
camera-type eye development |
GO:0043029 |
T cell homeostasis |
GO:0043234 |
protein complex |
GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
GO:0043565 |
sequence-specific DNA binding |
GO:0045077 |
negative regulation of interferon-gamma biosynthetic process |
GO:0045085 |
negative regulation of interleukin-2 biosynthetic process |
GO:0045892 |
negative regulation of transcription, DNA-dependent |
GO:0045893 |
positive regulation of transcription, DNA-dependent |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046007 |
negative regulation of activated T cell proliferation |
GO:0046872 |
metal ion binding |
GO:0046982 |
protein heterodimerization activity |
GO:0048286 |
lung alveolus development |
GO:0048294 |
negative regulation of isotype switching to IgE isotypes |
GO:0048302 |
regulation of isotype switching to IgG isotypes |
GO:0048745 |
smooth muscle tissue development |
GO:0050710 |
negative regulation of cytokine secretion |
GO:0050777 |
negative regulation of immune response |
GO:0050852 |
T cell receptor signaling pathway |
GO:0051059 |
NF-kappaB binding |
GO:0051525 |
NFAT protein binding |
GO:0060013 |
righting reflex |
GO:0060501 |
positive regulation of epithelial cell proliferation involved in lung morphogenesis |