Gene basic information
| LiverAtlas Gene ID |
HuLG009552 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
APH1A |
|
Synonyms |
6530402N02Rik|APHN1|APHN1A|CGIN78 |
|
Gene name |
anterior pharynx defective 1 homolog A (C. elegans) |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p36.13-q31.3 |
|
Known cancer genes |
Yes |
|
Protein products |
Gamma-secretase subunit APH-1A |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:29509
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001656 |
metanephros development |
|
GO:0004175 |
endopeptidase activity |
|
GO:0005515 |
protein binding |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006509 |
membrane protein ectodomain proteolysis |
|
GO:0006915 |
apoptosis |
|
GO:0007219 |
Notch signaling pathway |
|
GO:0007220 |
Notch receptor processing |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0016485 |
protein processing |
|
GO:0031293 |
membrane protein intracellular domain proteolysis |
|
GO:0032580 |
Golgi cisterna membrane |
|
GO:0042987 |
amyloid precursor protein catabolic process |
|
GO:0043085 |
positive regulation of catalytic activity |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
